Quick answer:Nurse Practitioners in South Carolina earn a median $123,290 per year, below the national median of $132,300 (BLS OEWS, May 2025). The state employs about 5,670 of them. Licensing runs through your state board of nursing.
Nurse Practitioner Pay and Employment in South Carolina at a Glance
Metric
South Carolina
National
Source
Median annual wage
$123,290
$132,300
BLS OEWS, May 2025
10th percentile
$97,080
$101,340
BLS OEWS, May 2025
25th percentile
$107,930
$117,990
BLS OEWS, May 2025
75th percentile
$132,220
$156,700
BLS OEWS, May 2025
90th percentile
$160,170
$174,420
BLS OEWS, May 2025
Employment
5,670
323,040
BLS OEWS, May 2025
Location quotient
1.18
1.00
BLS OEWS, May 2025
Projected change (2024-34)
not published by state
40.1%
BLS Employment Projections, 2024-34
How South Carolina Pay Compares to the Rest of the Country
The South Carolina median of $123,290 sits below the national median of $132,300 (BLS OEWS, May 2025). Percentiles matter more than the midpoint when you are deciding whether a degree pays for itself: the 10th percentile is roughly where people start, and the 90th is what the top of the local market looks like after years of experience.
A location quotient of 1.18 puts South Carolina well above the national average, so the work is noticeably more common here than in the typical state. That usually means a deeper job market and more room to change employers without relocating (BLS OEWS, May 2025). The measure compares how concentrated the occupation is here against the national average of 1.00.
Figures: BLS OEWS, May 2025. Clinical placement is local: graduate nursing programs require supervised hours completed in person, and preceptor availability tracks the local health system.
Nurse Practitioners Wages by Metro Area in South Carolina
According to the Bureau of Labor Statistics ( OES data), nurse practitioners wages in South Carolina vary by metro area.
Metro Area
Employment
Median Annual Wage
Avg. Annual Wage
Entry Level (10th pctile)
Experienced (90th pctile)
Charlotte-Concord-Gastonia
1,970
$130,310
$133,530
$107,350
$170,490
Greenville-Anderson-Greer
1,120
$119,280
$118,850
$81,910
$145,570
Charleston-North Charleston
1,050
$127,780
$126,750
$103,200
$157,170
Columbia
920
$118,470
$120,550
$97,010
$150,700
Augusta-Richmond County
500
$120,270
$120,060
$99,290
$151,200
Florence
270
$121,930
$127,670
$97,820
$156,830
Hilton Head Island-Bluffton-Port Royal
260
$119,130
$117,880
$98,630
$133,150
Myrtle Beach-Conway-North Myrtle Beach
260
$121,390
$119,990
$97,120
$154,630
Spartanburg
260
$121,120
$128,140
$103,270
$156,840
Sumter
80
$112,080
$115,400
$94,920
$132,260
Wages reflect survey data and vary based on experience, credentials, employer, and local market conditions. Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May .
All South Carolina Metro Areas With Published Data
Nurse practitioners are advanced practice registered nurses. The national framework is a graduate degree (MSN or DNP) from a program accredited by CCNE or ACEN, national certification through AANP or ANCC, and APRN licensure issued by the state board of nursing. How much a nurse practitioner may do independently - full, reduced or restricted practice authority - is set by each state and is one of the most consequential differences between them.
Requirements are set at state level and are amended periodically. Before you enroll in any program, confirm with your state board of nursing that the specific program you are considering satisfies the education requirement, and ask what it accepts from any training you have already completed. Get the answer in writing.
Earning the Degree While You Work
Most people reading this already have a job in the field, and the practical question is whether the credential can be earned without leaving it. Programs designed for working adults deliver the academic portion online or in the evening, while any labs, clinical hours or supervised field experience happen in person and locally. Prior college credit, military training, apprenticeship coursework and industry certifications can all shorten the path, so request a written transfer credit evaluation before you commit to any school.
Schools in our database near this area, ranked by BOC Score. The list favors schools with a related program on record, but program availability and delivery format change, so confirm directly with any school that it currently offers the program you want.
How We Rank Schools
We first gather the schools closest to the city or state page you are viewing, then rank that
local group by BOC Score, with the highest at the top. The BOC Score is computed from federal
IPEDS and College Scorecard data; schools without enough data to score appear last.
LOCAL RANK
Location / proximity to this page
Defines the local group
Graduation rate
30%
Median earnings, 10 years after entry
25%
Average net price (lower is better)
20%
Retention rate
15%
Fully online availability
10%
Schools without enough federal outcome data appear after ranked schools, without a score.
Advertising never affects these rankings. Read the full methodology.
How much do nurse practitioners make in South Carolina?
The median annual wage for nurse practitioners in South Carolina is $123,290, below the national median of $132,300 (BLS OEWS, May 2025). The middle of the range runs from $107,930 at the 25th percentile to $132,220 at the 75th.
How many nurse practitioners work in South Carolina?
South Carolina holds about 5,670 nurse practitioner jobs (BLS OEWS, May 2025). Nationally the occupation employs 323,040, and BLS projects about 29,500 openings per year through 2034 (BLS Employment Projections, 2024-34).
Do I need a license to work as a nurse practitioner in South Carolina?
Nurse practitioners are advanced practice registered nurses. The national framework is a graduate degree (MSN or DNP) from a program accredited by CCNE or ACEN, national certification through AANP or ANCC, and APRN licensure issued by the state board of nursing. How much a nurse practitioner may do independently - full, reduced or restricted practice authority - is set by each state and is one of the most consequential differences between them. Requirements are set at the state level and change periodically, so confirm the current rules with your state board of nursing before you enroll in any program.
Can I earn a MSN or DNP online while working in South Carolina?
Often yes. Programs built for working adults deliver coursework online or in the evenings, though any required labs, clinical hours or supervised field experience are completed in person. Confirm that the program's accreditation satisfies your state board of nursing.
What is the highest-paying area of South Carolina for nurse practitioners?
Among South Carolina metro areas with published data, Charleston reports the highest median at $127,780 (BLS OEWS, May 2025).
Is South Carolina a good state for nurse practitioners?
On pay, the state median of $123,290 sits below the national $132,300 (BLS OEWS, May 2025). A location quotient of 1.18 means the occupation is more concentrated here than in the average state. Weigh that against cost of living and how concentrated the work is near where you actually want to live.
U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics (OEWS), May 2025 - Nurse Practitioners (SOC 29-1171), national, state and metropolitan estimates
U.S. Bureau of Labor Statistics, Employment Projections, 2024-34
U.S. Bureau of Labor Statistics, Occupational Outlook Handbook - education and licensing requirements
Wage and employment figures describe the occupation as measured by the Bureau of Labor Statistics, not the graduates of any particular program, and individual outcomes may vary. Licensing rules change; confirm current requirements with the responsible state board before enrolling.
About this guide: Researched and written by the TradeCareerPath Editorial Team. Our editorial team researches and sources every trade school and career guide using federal labor and education data, including BLS OEWS and Employment Projections, DOL apprenticeship records, IPEDS, College Scorecard, and state licensing boards. We follow the editorial standards documented at /editorial-policy/.
